Corpus ID: 231648073

Effective connectivity determines the critical dynamics of biochemical networks

  title={Effective connectivity determines the critical dynamics of biochemical networks},
  author={Santosh Manicka and Manuel Marques-Pita and Luis Mateus Rocha},
Living systems operate in a critical dynamical regime—between order and chaos—where they are both resilient to perturbation, and flexible enough to evolve. To characterize such critical dynamics, the established structural theory of criticality uses automata network connectivity and node bias (to be on or off) as tuning parameters. This parsimony in the number of parameters needed sometimes leads to uncertain predictions about the dynamical regime of both random and systems biology models of… Expand

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