Effective chemokine secretion by dendritic cells and expansion of cross-presenting CD4-/CD8+ dendritic cells define a protective phenotype in the mouse model of coxsackievirus myocarditis.

@article{Weinzierl2008EffectiveCS,
  title={Effective chemokine secretion by dendritic cells and expansion of cross-presenting CD4-/CD8+ dendritic cells define a protective phenotype in the mouse model of coxsackievirus myocarditis.},
  author={Andreas Oliver Weinzierl and Gudrun Szalay and Hartwig Wolburg and Martina Sauter and Hans-Georg Rammensee and Reinhard Kandolf and Stefan Stevanovi{\'c} and Karin Klingel},
  journal={Journal of virology},
  year={2008},
  volume={82 16},
  pages={8149-60}
}
Enteroviruses such as coxsackievirus B3 (CVB3) are able to induce lethal acute and chronic myocarditis. In resistant C57BL/6 mice, CVB3 myocarditis is abrogated by T-cell-dependent mechanisms, whereas major histocompatibility complex (MHC)-matched permissive A.BY/SnJ mice develop chronic myocarditis based on virus persistence. To define the role of T-cell… CONTINUE READING