Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.

@article{Ahern2013EffectiveAW,
  title={Effective analgesia with low-dose ketamine and reduced dose hydromorphone in ED patients with severe pain.},
  author={Terence L. Ahern and Andrew Avery Herring and Michael B. Stone and Bradley W. Frazee},
  journal={The American journal of emergency medicine},
  year={2013},
  volume={31 5},
  pages={847-51}
}
OBJECTIVE We assessed the analgesic effect and feasibility of low-dose ketamine combined with a reduced dose of hydromorphone for emergency department (ED) patients with severe pain. METHODS This was a prospective observational study of adult patients with severe pain at an urban public hospital. We administered 0.5 mg of intravenous (IV) hydromorphone and 15 mg of IV ketamine, followed by optional 1 mg hydromorphone IV at 15 and 30 minutes. Pain intensity was assessed at 12 intervals over… CONTINUE READING