Effective Photoprotection of Human Skin against Infrared A Radiation by Topically Applied Antioxidants: Results from a Vehicle Controlled, Double‐Blind, Randomized Study

  title={Effective Photoprotection of Human Skin against Infrared A Radiation by Topically Applied Antioxidants: Results from a Vehicle Controlled, Double‐Blind, Randomized Study},
  author={S Grether-Beck and Alessandra Marini and Thomas Jaenicke and Jean Krutmann},
  journal={Photochemistry and Photobiology},
Infrared A radiation (IRA) from solar sunlight contributes to photoaging of human skin, e.g. by upregulating MMP‐1 expression in dermal fibroblasts, indicating the need for photoprotection of human skin against IRA. Up to now, however, there has been no controlled study to show that effective protection of human skin against IRA radiation is possible. Here, we have conducted a randomized, controlled, double‐blinded prospective study in 30 healthy volunteers to assess the capacity of an SPF 30… 
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  • Methods
  • 2001
Analysis of relative gene expression data using real-time quantitative PCR and the 2-DDCT Method. Methods 25, 402–408
  • 2001