Effective, Broad Spectrum Control of Virulent Bacterial Infections Using Cationic DNA Liposome Complexes Combined with Bacterial Antigens

@inproceedings{Ireland2010EffectiveBS,
  title={Effective, Broad Spectrum Control of Virulent Bacterial Infections Using Cationic DNA Liposome Complexes Combined with Bacterial Antigens},
  author={Robin Ireland and Norma Olivares-Zavaleta and Jonathan Mark Warawa and Frank C Gherardini and Clayton O. Jarrett and B Joseph Hinnebusch and John T. Belisle and Jeffery Fairman and Catharine M. Bosio},
  booktitle={PLoS pathogens},
  year={2010}
}
Protection against virulent pathogens that cause acute, fatal disease is often hampered by development of microbial resistance to traditional chemotherapeutics. Further, most successful pathogens possess an array of immune evasion strategies to avoid detection and elimination by the host. Development of novel, immunomodulatory prophylaxes that target the host immune system, rather than the invading microbe, could serve as effective alternatives to traditional chemotherapies. Here we describe… CONTINUE READING
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