Effect-site half-time for burst suppression is longer than for hypnosis during anaesthesia with sevoflurane.
@article{Kennedy2008EffectsiteHF, title={Effect-site half-time for burst suppression is longer than for hypnosis during anaesthesia with sevoflurane.}, author={R. Ross Kennedy and Christine Minto and A Seethepalli}, journal={British journal of anaesthesia}, year={2008}, volume={100 1}, pages={ 72-7 } }
- Published 2008 in British journal of anaesthesia
BACKGROUND
The relationship between measures of drug effect such as bispectral index (BIS) and end-tidal (ET) levels of anaesthetic agents is described by the 'effect site equilibrium half-time', t(1/2)(ke0). There are limited data available on sevoflurane t(1/2)(ke0) during routine anaesthesia and surgery. Preliminary observations suggested t(1/2)(ke0) for the degree of hypnosis as estimated by BIS is different from that for burst suppression of the electroencephalograph, occurring at 'deep… CONTINUE READING