Effect of zinc supplementation on insulin resistance and components of the metabolic syndrome in prepubertal obese children

  title={Effect of zinc supplementation on insulin resistance and components of the metabolic syndrome in prepubertal obese children},
  author={Mahin Hashemipour and Roya Kelishadi and Javad Shapouri and Nizal Sarrafzadegan and Masoud Amini and Naser Tavakoli and Ahmad Movahedian-Attar and Parisa Mirmoghtadaee and Parinaz Poursafa},
OBJECTIVEZinc, an essential trace element and a component of many enzymes, is involved in the synthesis, storage and release of insulin. The aim of the present study was to assess the effect of zinc supplementation on insulin resistance and components of the metabolic syndrome in prepubertal obese children.DESIGNThis triple-masked, randomized, placebo-controlled cross-over trial was conducted among 60 obese Iranian children in 2008. Pertinent clinical findings, fasting serum glucose, insulin… 

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