Effect of zinc supplementation on child mortality

@article{Lazzerini2007EffectOZ,
  title={Effect of zinc supplementation on child mortality},
  author={Marzia Lazzerini},
  journal={The Lancet},
  year={2007},
  volume={370},
  pages={1194-1195}
}
Micronutrients for the Prevention and Treatment of Diarrhea in Children in Low- and Middle-Income Countries
TLDR
Evidence supports a benefit of zinc supplementation for prevention and treatment of diarrhea, although this is limited to children over 6 months of age and in countries with moderate to high levels of zinc deficiency.
Oral zinc provision in acute diarrhea
  • M. Lazzerini
  • Medicine
    Current opinion in clinical nutrition and metabolic care
  • 2016
TLDR
Current literature supports the use of oral zinc in treating diarrhea in children older than 6 months, especially if at risk of zinc deficiency, such as children with poor diets exposed to recurrent gastrointestinal infections.
Global child health: promises made to children-not yet kept.
  • B. Duncan
  • Political Science, Medicine
    Advances in pediatrics
  • 2009
Bioequivalence of Micronutrient Powders to Conventional Fortification on Zinc Status of Children Aged 6-36 Months in Thika Informal Settlements, Kenya
A research thesis submitted in partial fulfillment for the degree of doctor of philosophy in the school of applied human sciences of Kenyatta University, November, 2016

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Zinc during and in convalescence from diarrhea has no demonstrable effect on subsequent morbidity and anthropometric status among infants <6 mo of age.
TLDR
Young infants do not appear to benefit from 2 wk of zinc, unlike what has been observed among older children.
Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries: pooled analysis of randomized controlled trials.
TLDR
Zinc supplementation reduces the duration and severity of acute and persistent diarrhoea and in persistent diarrhea.
Role of Zinc Administration in Prevention of Childhood Diarrhea and Respiratory Illnesses: A Meta-analysis
TLDR
Zinc supplementation reduced significantly the frequency and severity of diarrhea and respiratory illnesses and the duration of diarrheal morbidity and the presence of significant heterogeneity and of publication bias indicate the need for larger, high-quality studies to identify subpopulations most likely to benefit.
Zinc Supplementation for the Treatment of Diarrhea in Infants in Pakistan, India and Ethiopia
TLDR
Young infants do not appear to benefit from zinc supplementation for the treatment of diarrhea, and rates of vomiting were similar in the zinc and placebo groups.
Effect of supplemental zinc on the growth and serum zinc concentrations of prepubertal children: a meta-analysis of randomized controlled trials.
TLDR
Interventions to improve children's zinc nutriture should be considered in populations at risk of zinc deficiency, especially where there are elevated rates of underweight or stunting.
Comparative quantification of health risks. Global and regional burden of disease attributable to selected major risk factors. Volume 1.
TLDR
This book provides a comprehensive assessment of the scientific evidence on prevalence and hazards, and the resulting health effects, of a range of exposures that are known to be hazardous to human health, including childhood and maternal undernutrition, nutritional and physiological risk factors for adult health, addictive substances, sexual and reproductive health, and risks in the physical environments of households and communities.
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