Effect of x-irradiation on immunocompetency of T-lymphocytes.


Effect of x-irradiation on various aspects of cell-mediated immune reactions is studied. The irradiated splenic lymphocytes could transform to blast cells upon stimulation with PHA, but could not divide into small lymphocytes. It was concluded that irradiation at doses higher than 500 rads inhibits the differentiation of lymphocytes to effector cells upon… (More)