Effect of white matter hyperintensities on cortical cerebral blood volume using perfusion MRI.

@article{Wen2004EffectOW,
  title={Effect of white matter hyperintensities on cortical cerebral blood volume using perfusion MRI.},
  author={Wei Wen and Perminder S. Sachdev and Ron Shnier and Henry Brodaty},
  journal={NeuroImage},
  year={2004},
  volume={21 4},
  pages={1350-6}
}
White matter hyperintensities (WMHs) are commonly seen on brain magnetic resonance imaging (MRI) scans of elderly individuals, but their functional significance remains controversial. We used perfusion-weighted MRI to determine the impact of WMHs on cortical regional cerebral blood volume (rCBV). We studied 24 elderly stroke patients and 27 control subjects with conventional MRI which included T2-weighted FLAIR coronal slices through whole brain and gadolinium-DTPA (0.2 mmol/kg)-based perfusion… CONTINUE READING