Effect of water flow and chemical environment on microbiota growth and composition in the human colon.

@article{Cremer2017EffectOW,
  title={Effect of water flow and chemical environment on microbiota growth and composition in the human colon.},
  author={Jonas Cremer and Markus Arnoldini and Terence Hwa},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2017},
  volume={114 25},
  pages={6438-6443}
}
The human gut harbors a dynamic microbial community whose composition bears great importance for the health of the host. Here, we investigate how colonic physiology impacts bacterial growth, which ultimately dictates microbiota composition. Combining measurements of bacterial physiology with analysis of published data on human physiology into a quantitative, comprehensive modeling framework, we show how water flow in the colon, in concert with other physiological factors, determine the… CONTINUE READING
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