Effect of warfarin anticoagulation on thrombin generation in patients with idiopathic pulmonary arterial hypertension.

@article{Jansa2010EffectOW,
  title={Effect of warfarin anticoagulation on thrombin generation in patients with idiopathic pulmonary arterial hypertension.},
  author={Pavel Jansa and Ingrid Hrachovinov{\'a} and David Ambro{\vz} and Jana Maresov{\'a} and Pavel Pol{\'a}{\vc}ek and Iveta {\vS}imkov{\'a} and Ale{\vs} Linhart and Michael Aschermann},
  journal={Bratislavske lekarske listy},
  year={2010},
  volume={111 11},
  pages={595-8}
}
BACKGROUND Oral anticoagulant therapy is recommended for patients with pulmonary arterial hypertension (PAH). The rationale for the use of anticoagulant treatment is based on thrombophylic predisposition in PAH and improvement of survival in patients treated with anticoagulation. However, the target INR value has not been evaluated. The aim of this study was to analyze thrombin generation in patients with PAH treated with warfarin anticoagulation. METHODS The study was performed in 58… CONTINUE READING