Effect of viral RNase H on the avian sarcoma viral genome during early transcription in vitro.

@article{Friedrich1979EffectOV,
  title={Effect of viral RNase H on the avian sarcoma viral genome during early transcription in vitro.},
  author={Rainer Friedrich and Karin Moelling},
  journal={Journal of virology},
  year={1979},
  volume={31 3},
  pages={630-8}
}
We investigated the influence of viral RNase H on the transcription of the avian sarcoma virus RNA in a virion-associated reaction. The ability of RNase H to degrade the RNA moiety of the initially formed RNA-DNA hybrid at the 5' end of the viral genome was found to be greatly dependent on the exact concentration of nonionic detergent used to activate the… CONTINUE READING