Effect of vasopressors on organ blood flow during endotoxin shock in pigs.

@article{Breslow1987EffectOV,
  title={Effect of vasopressors on organ blood flow during endotoxin shock in pigs.},
  author={Michael Breslow and Charles F. Miller and Stephen D. Parker and A T Walman and Richard J. Traystman},
  journal={The American journal of physiology},
  year={1987},
  volume={252 2 Pt 2},
  pages={H291-300}
}
A volume-resuscitated porcine endotoxin shock model was used to evaluate the effect on organ blood flow of increasing systemic arterial blood pressure with vasopressors. Administration of 0.05-0.2 mg/kg of Escherichia coli endotoxin (E) reduced mean arterial blood pressure (MAP) to 50 mmHg, decreased systemic vascular resistance to 50% of control, and did not change cardiac output or heart rate. Blood flow to brain, kidney, spleen, and skeletal muscle was reduced during endotoxin shock, but… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

Similar Papers

Loading similar papers…