Effect of vasoconstrictor pre-treatment on obstruction, secretion and sneezing after nasal challenge with threshold and suprathreshold allergen doses.

@article{Brooks1993EffectOV,
  title={Effect of vasoconstrictor pre-treatment on obstruction, secretion and sneezing after nasal challenge with threshold and suprathreshold allergen doses.},
  author={Carter D. Brooks and Kalipada Karl and Steven F. Francom},
  journal={Rhinology},
  year={1993},
  volume={31 4},
  pages={165-8}
}
Acute nasal allergen challenge produces airway obstruction which varies in amount and timing with the allergen dose delivered. To see whether different mechanisms might contribute variably to mucosal swelling with different amounts of allergen, we challenged sensitive volunteers with threshold and 10-times threshold allergen doses, with and without topical… CONTINUE READING