Effect of varying the mitomycin-C treatment area in glaucoma filtration surgery in the rabbit.

@article{Cordeiro1997EffectOV,
  title={Effect of varying the mitomycin-C treatment area in glaucoma filtration surgery in the rabbit.},
  author={Maria Francesca Cordeiro and Peter H Constable and Robert A. Alexander and Shomi Shanker Bhattacharya and Peng T. Khaw},
  journal={Investigative ophthalmology & visual science},
  year={1997},
  volume={38 8},
  pages={1639-46}
}
PURPOSE To investigate the effect of varying the treatment area of subconjunctival mitomycin-C (MMC) using an adapted rabbit model of filtration surgery. METHODS Twenty-four New Zealand White rabbits underwent filtration surgery, with random allocation to one of three treatments: 5-minute subconjunctival applications of MMC (0.4 mg/ml) with either a large (8 x 10 mm) or small (4 x 2 mm) sponge or no treatment (control). Drainage was achieved by placing an intravenous cannula through a scleral… CONTINUE READING