Effect of various doses of recombinant human thyrotropin on the thyroid radioactive iodine uptake and serum levels of thyroid hormones and thyroglobulin in normal subjects.

@article{Torres2001EffectOV,
  title={Effect of various doses of recombinant human thyrotropin on the thyroid radioactive iodine uptake and serum levels of thyroid hormones and thyroglobulin in normal subjects.},
  author={Mira Sofia Torres and Luis Enrique Soto Ram{\'i}rez and P H Simkin and Lewis E. Braverman and Charles H. Emerson},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2001},
  volume={86 4},
  pages={1660-4}
}
Recombinant human TSH (rhTSH), usually given as 0.9-mg doses im on 2 successive days, increases serum thyroglobulin (Tg) and radioactive iodine uptake (RAIU) in residual thyroid tissue in patients with thyroid cancer. We previously reported that a single, relatively low dose of rhTSH (0.1 mg im) is a potent stimulator of T(4), T(3), and Tg secretion in normal subjects. The present study describes the effects of higher doses of rhTSH on thyroid hormone and Tg secretion. Six normal subjects for… CONTINUE READING