Effect of various Viperidae and Crotalidae snake venoms on endothelial cells in vitro.

Abstract

The effect of various crotalid and viperid venoms at 10, 50 and 100 micrograms/ml was examined on bovine and murine endothelial cells in vitro. The venoms caused the cells to lose their processes, leading to the appearance of spaces which were gradually enlarged between clusters of cells. The cells became round and finally detached from the substrate. This… (More)

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