Effect of valsartan versus lisinopril on peritoneal sclerosis in rats.

@article{Duman2005EffectOV,
  title={Effect of valsartan versus lisinopril on peritoneal sclerosis in rats.},
  author={Soner Duman and Sait Şen and Can Duman and Dimitrios George Oreopoulos},
  journal={The International journal of artificial organs},
  year={2005},
  volume={28 2},
  pages={
          156-63
        }
}
BACKGROUND Peritoneal sclerosis (PS) is one of the most serious causes of failure in long-term peritoneal dialysis. Angiotensin II is known to promote fibrosis and inflammation in various tissues. We previously showed that ACE inhibitors (ACEIs) have beneficial effects on hypertonic PD solutions (3.86% PD) induced peritoneal alterations. The aim of this study is to compare the effects of an ACEI and a receptor blocker on peritoneal alterations induced by hypertonic PD solutions in rats… CONTINUE READING

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