Effect of valerian, Valeriana edulis, on sleep difficulties in children with intellectual deficits: randomised trial.

  title={Effect of valerian, Valeriana edulis, on sleep difficulties in children with intellectual deficits: randomised trial.},
  author={A. J. Francis and Robert J. Dempster},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  volume={9 4},
  • A. J. Francis, R. Dempster
  • Published 2002
  • Medicine, Psychology
  • Phytomedicine : international journal of phytotherapy and phytopharmacology
Serious sleep problems are common in children with an intellectual deficit (ID), and are often the source of much distress for both the child and caregivers. As yet, no satisfactory long-term treatment exists for intransigent sleep difficulties in children with an ID. Valerian, Valeriana spp., has been used for thousands of years to induce relaxation and sleep. Scientific investigation of valerian's sleep promoting ability in humans, whilst limited, has yielded promising findings. This initial… 

Figures and Tables from this paper

Valerian for Sleep: A Systematic Review and

The available evidence suggests that valerian might improve sleep quality without producing side effects, and future studies should assess a range of doses of standardized preparations of Valerian and include standard measures of sleep quality and safety.

Insomnia: the Sleeping Giant of Pediatric Public Health

Behavioral techniques, such as cognitive behavior therapy for insomnia and sleep hygiene education, should remain the first line of treatment and melatonin, a dietary supplement, may be effective.

Valeriana en el tratamiento a largo plazo del insomnio

The key advantage of valerian is its capability to reduce the slow wave sleep latency and increase its percentage without causing relevant secondary effects or dependence.

yperactivity , concentration difficulties and impulsiveness improve uring seven weeks ’ treatment with valerian root and lemon balm xtracts in primary school children

In primary school children with restlessness, concentration difficulties and impulsiveness treatment with WS® 1014 and WS® 1303 (Sandrin®) provides a viable option in addition to counseling and education.

Sleep disorders in children and adolescents with learning disabilities and their management

A start at an evidence‐based background for practical and rational prescribing in this area of common childhood psychopathology is attempted, focusing on important clinical issues and predicaments.

Valerian Root in Treating Sleep Problems and Associated Disorders—A Systematic Review and Meta-Analysis

Valerian could be a safe and effective herb to promote sleep and prevent associated disorders, however, due to the presence of multiple active constituents and relatively unstable nature of some of the active constituents, it may be necessary to revise the quality control processes, including standardization methods and shelf life.



Effect of valerian on human sleep

The results indicate that the aqueous valerian extract exerts a mild hypnotic action in healthy, young subjects, and suggests a dose-dependent effect.

Critical evaluation of the effect of valerian extract on sleep structure and sleep quality.

Treatment with a herbal extract of radix valerianae demonstrated positive effects on sleep structure and sleep perception of insomnia patients, and can therefore be recommended for the treatment of patients with mild psychophysiological insomnia.

Severe sleep disturbance and daytime challenging behaviour in children with severe learning disabilities.

  • L. WiggsG. Stores
  • Medicine, Psychology
    Journal of intellectual disability research : JIDR
  • 1996
Children with sleep problems showed significantly more types of challenging behaviour and challenging behaviour of a greater severity than children without sleep problems, resulting in management difficulties for carers throughout the 24-h period.

Aqueous extract of valerian reduces latency to fall asleep in man.

Using the first period of 5 consecutive minutes without movement as a criterion of sleep onset, there was a significant decrease in sleep latency with 450 mg valerian compared to placebo.

A community survey of characteristics of one- to two- year-olds with sleep disruptions.

  • N. Richman
  • Psychology
    Journal of the American Academy of Child Psychiatry
  • 1981

Beyond Benzodiazepines: Alternative Pharmacologic Agents for the Treatment of Insomnia

Novel nonbenzodiazepine hypnotics including zolpidem, zopiclone, and zaleplon, as well as nonprescription products such as valerian and melatonin, are reviewed in detail to provide an overview of the pharmacologic therapy of insomnia.

Psychotropic effects of Japanese valerian root extract.

It is indicated that valerian extract acts on the central nervous system and may be an antidepressant and reversed reserpine-induced hypothermia in mice.

Efficacy and safety of herbal stimulants and sedatives in sleep disorders.

Valerian and kava have received the most research attention; both have decreased sleep onset time and promoted deeper sleep in small studies, andKava also shows anxiolytic effects.

Double blind study of a Valerian preparation

Prevalence of behaviour problems in 3-year-old children: an epidemiological study in a London borough.

It was found that 7 per cent of 3-year-old children living in a North London Borough had a behaviour problem winch was moderate or severe, and boys were significantly more likely to be overactive, to be wetting at night and during the day, to have relapsed in sphincter control after a period of being clean or dry.