Effect of urine component on leukocyte chemiluminescence response.

  title={Effect of urine component on leukocyte chemiluminescence response.},
  author={Shinji Kubo and Tetsuro Matsumoto and M. Sakumoto and O. Mochida and Yoichi Abe and Joichi Kumazawa},
  journal={Renal failure},
  volume={20 1},
In the urine, the function of polymorphonuclear leukocytes (PMNs) is thought to be impaired because of the high osmolality and low pH along with a high concentration of inorganic salts. We investigated the effect of the properties of urine and its components on the chemiluminescence (CL) response of PMNs. This was helped by using an artificial urine. The CL response was measured by automatic luminometer following stimulation of phorbol myristate acetate. We found the CL response of PMNs to be… CONTINUE READING