Effect of up-regulation of NMDA receptors on cerebral O2 consumption and blood flow in rat.

Abstract

We tested the hypothesis that cerebrocortical blood flow and O2 consumption would be proportional to an up-regulated number of functional N-methyl-D-aspartate (NMDA) receptors. Previous work had shown a relationship between cerebral metabolism and NMDA receptor activity. We increased the specific binding to NMDA receptors in the cerebral cortex, from 2.2… (More)

Topics

  • Presentations referencing similar topics