Effect of tyramine in migraine: a double-blind study.

  title={Effect of tyramine in migraine: a double-blind study.},
  author={Allen Moffett and Michael Swash and Dr. William Scott},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  volume={35 4},
The incidence of headache and changes in the EEG after tyramine were studied in 25 migrainous patients in a double-blind placebo-controlled investigation. There were three groups of patients: the first had migraine alone, the second had migraine and epilepsy, and the third had migraine which was precipitated by food substances containing tyramine. Psychological tests showed that all the patients were more neurotic, more introverted, and more obsessional than normal subjects. Headache occurred… CONTINUE READING