Effect of tunicamycin on the glycosylation of rhodopsin.

@article{Plantner1980EffectOT,
  title={Effect of tunicamycin on the glycosylation of rhodopsin.},
  author={James J. Plantner and Louis Poncz and Edward L. Kean},
  journal={Archives of biochemistry and biophysics},
  year={1980},
  volume={201 2},
  pages={
          527-32
        }
}
Abstract The incorporation of [3H]glucosamine, [3H]mannose, and [35S]methionine into rhodopsin was investigated in retinas which had been incubated in the presence and absence of the antibiotic, tunicamycin. In its presence, the incorporation of glucosamine was inhibited 70% and mannose, 96% compared to controls. In the presence of tunicamycin the attachment of glucosamine to core-region sites was virtually eliminated. The formation of unglycosylated rhodopsin was also indicated by sodium… Expand
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