Effect of tubular inhomogeneities on feedback-mediated dynamics of a model of a thick ascending limb.


One of the key mechanisms that mediate renal autoregulation is the tubuloglomerular feedback (TGF) system, which is a negative feedback loop in the kidney that balances glomerular filtration with tubular reabsorptive capacity. Tubular fluid flow, NaCl concentration and other related variables are known to exhibit TGF-mediated oscillations. In this study, we… (More)
DOI: 10.1093/imammb/dqs020