Effect of triiodothyronine on muscle cell differentiation and blood glucose level in hyperglycemic KK mice.

@article{Shimokawa1997EffectOT,
  title={Effect of triiodothyronine on muscle cell differentiation and blood glucose level in hyperglycemic KK mice.},
  author={Teruhiko Shimokawa and Miyuki Kato and K Shioduka and Junko Irie and Osamu Ezaki},
  journal={Biochemical and biophysical research communications},
  year={1997},
  volume={235 3},
  pages={790-3}
}
KK mice are genetically diabetic animals, showing glucose intolerance and insulin resistance. We examined the effects of 3,3',5-triiodo-L-thyronine (T3) on the blood glucose level and on mRNA levels of muscle cell differentiation markers in hyperglycemic KK mice. T3 treatment (T1, 1 mg; T3, 3 mg; T10, 10 mg/kg/day) of KK mice for 4 days caused a decrease in… CONTINUE READING