Effect of treatment with methotrexate and coal tar on adipokine levels and indices of insulin resistance and sensitivity in patients with psoriasis vulgaris.

@article{Rajappa2015EffectOT,
  title={Effect of treatment with methotrexate and coal tar on adipokine levels and indices of insulin resistance and sensitivity in patients with psoriasis vulgaris.},
  author={Medha Rajappa and Shenoy D. Rathika and Malathi Munisamy and Laxmisha Chandrashekar and Devinder M Thappa},
  journal={Journal of the European Academy of Dermatology and Venereology : JEADV},
  year={2015},
  volume={29 1},
  pages={69-76}
}
BACKGROUND AND OBJECTIVES Recent studies have implicated adipokines in the pathogenesis of the immune-mediated inflammatory disease, psoriasis and its associated comorbidities. Hence, we undertook to study adipokine levels and indices of insulin resistance and sensitivity in patients with psoriasis vulgaris, in comparison with controls and their association with disease severity and response to therapy. METHODS Sixty cases of psoriasis vulgaris and 60 age- and gender-matched healthy controls… CONTINUE READING

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