Effect of treatment with geraniol on ovalbumin-induced allergic asthma in mice.

@article{Xue2016EffectOT,
  title={Effect of treatment with geraniol on ovalbumin-induced allergic asthma in mice.},
  author={Zheng Xue and Xin-guang Zhang and Jie Wu and Wan-Chao Xu and Li-qing Li and Fei Liu and Jian-er Yu},
  journal={Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology},
  year={2016},
  volume={116 6},
  pages={
          506-13
        }
}
BACKGROUND Asthma, a complex highly prevalent airway disease, is a major public health problem for which current treatment options are inadequate. OBJECTIVE To evaluate the antiasthma activity of geraniol and investigate its underlying molecular mechanisms. METHODS In a standard experimental asthma model, Balb/c mice were sensitized with ovalbumin, treated with geraniol (100 or 200 mg/kg) or a vehicle control, during ovalbumin challenge. RESULTS Treatment of ovalbumin-sensitized… CONTINUE READING
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