Effect of treatment of hyperuricemia with allopurinol on blood pressure, creatinine clearence, and proteinuria in patients with normal renal functions

@article{Kanbay2007EffectOT,
  title={Effect of treatment of hyperuricemia with allopurinol on blood pressure, creatinine clearence, and proteinuria in patients with normal renal functions},
  author={Mehmet Kanbay and Adem Ozkara and Yusuf Selçoki and Bunyamin Isik and Faruk Turgut and N{\"u}ket Bavbek and Ebru Uz and Ali Akcay and Ramazan Yiğitoğlu and Adrian Covic},
  journal={International Urology and Nephrology},
  year={2007},
  volume={39},
  pages={1227-1233}
}
Hyperuricemia has been associated with the development of hypertension, cardiovascular, and renal disease. However, there is no data about the effect of lowering uric acid level on hypertension, renal function, and proteinuria in patients with glomerular filtration rate (GFR) >60 ml/min. We therefore conducted a prospective study to investigate the benefits of allopurinol treatment in hyperuricemic patients with normal renal function. Forty-eight hyperuricemic and 21 normouricemic patients were… CONTINUE READING

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