Effect of traumatic brain injury on mouse spatial and nonspatial learning in the Barnes circular maze.

@article{Fox1998EffectOT,
  title={Effect of traumatic brain injury on mouse spatial and nonspatial learning in the Barnes circular maze.},
  author={Gerard B. Fox and Lei Fan and R{\'e}gis Levasseur and Alan I. Faden},
  journal={Journal of neurotrauma},
  year={1998},
  volume={15 12},
  pages={1037-46}
}
Controlled cortical impact (CCI) is a relatively new model of traumatic brain injury in the mouse, which, in combination with behavioral and histological methods, has potential for elucidating underlying mechanisms of neurodegeneration using genetically altered animals. Previously, we have demonstrated impaired spatial learning in a water maze task following CCI injury at a moderate level. There are many difficulties associated with this task, however, such as stress, physical demand, and the… CONTINUE READING

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