Effect of transtympanic injection of steroids on cochlear blood flow, auditory sensitivity, and histology in the guinea pig.

@article{Shirwany1998EffectOT,
  title={Effect of transtympanic injection of steroids on cochlear blood flow, auditory sensitivity, and histology in the guinea pig.},
  author={Najeeb A. Shirwany and Michael D. Rice Stephen B. Seidman and Wenxue Tang},
  journal={The American journal of otology},
  year={1998},
  volume={19 2},
  pages={230-5}
}
HYPOTHESIS Transtympanic application of steroids is not harmful to the inner ear. BACKGROUND Steroids are routinely used to treat inner ear pathologies, such as sudden sensorineural hearing loss and autoimmune inner ear disease. The transtympanic route has received increased attention as it can lead to higher levels in tissue and nearly eliminate systemic effects. There has been concern over the safety of applying these drugs directly to the inner ear. METHODS This study investigates the… CONTINUE READING

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