Effect of transdermal nicotine administration on exercise endurance in men

@article{Mndel2006EffectOT,
  title={Effect of transdermal nicotine administration on exercise endurance in men},
  author={Toby M{\"u}ndel and David A Jones},
  journal={Experimental Physiology},
  year={2006},
  volume={91}
}
Nicotine is widely reported to increase alertness, improve co‐ordination and enhance cognitive performance; however, to our knowledge there have been no attempts to replicate these findings in relation to exercise endurance. The purpose of this study was to determine the effects nicotine might have on cycling endurance, perception of exertion and a range of physiological variables. With local ethics committee approval and having obtained informed consent, 12 healthy, non‐smoking men (22 ± 3… 
Effect of nicotine on repeated bouts of anaerobic exercise in nicotine naïve individuals
TLDR
It was concluded that oral-dispersible nicotine strips increase repeated anaerobic performance, possibly through strong sympathetic stimulation, as evident by significant elevation of cardiovascular parameters.
Nicotine Supplementation Does Not Influence Performance of a 1h Cycling Time-Trial in Trained Males
TLDR
It is determined that nicotine administration, whether via gum or transdermal patch, did not exert an ergogenic or ergolytic effect on self-paced cycling performance of ∼1 h and systemic delivery of nicotine was greatest when using a transderm patch.
The effects of oral smokeless tobacco administration on endurance performance
TLDR
It was showed that muscular and cerebral oxygenation increased significantly with snus administration during an endurance exercise until exhaustion, but this did not affect fatigue perception and TTE, and snus could not be considered an ergogenic substance in non-tobacco users.
The Effects of Transdermal Nicotine Patches on the Cardiorespiratory and Lactate Responses During Exercise from Light to Moderate Intensity: Implications for Exercise Prescription during Smoking Cessation
TLDR
The study results will guide clinicians or health professionals when prescribing exercise programs combined with TNPs for healthy young smokers, and the HR during exercise was greater at light to moderate intensity with a TNP.
Nicotine and exercise performance: another tool in the arsenal or curse for anti-doping?
TLDR
It is found that following oral consumption of 5 mg of nicotine, athletes who are nicotine naïve significantly increased their peak (and average) power output, as well as heart rate and blood pressure, which they attribute to nicotine’s sympathomimetic effect.
Nicotine effects on exercise performance and physiological responses in nicotine‐naïve individuals: a systematic review
TLDR
While there is strong evidence of nicotine‐induced changes in physiological function that would benefit physical performance, beneficial effects have only been reported on leg extensor torque and endurance performance by one study each and there is need for more research with strong methodological quality to definitively evaluate nicotine's potential as an ergogenic aid.
A Randomised, Placebo-Controlled, Crossover Study Investigating the Effects of Nicotine Gum on Strength, Power and Anaerobic Performance in Nicotine-Naïve, Active Males
TLDR
Chewing low-dose nicotine gum 20 min prior to exercise significantly improved leg extensor torque but did not affect counter-movement jump height or Wingate performance compared to a placebo, whilst there were minimal effects of the 4 mg nicotine gum on the performance parameters measured.
Exercise performance increase in smokeless tobacco‐user athletes after overnight nicotine abstinence
TLDR
Considering that twelve hours of abstinence from snus‐contained nicotine affected metabolic, cardiovascular and muscular tissue oxygenation, it is suggested that snus administration at test time might relieve these withdrawal changes and yield an increase in time to exhaustion.
The Acute Effect of Nicotine Intake on Anaerobic Exercise Performance
TLDR
This study evaluates whether nicotine, received in the form of sublingual tablets (4 mg), increases any of the parameters of the 30-second Wingate anaerobic test, which is used for evaluating short-term maximum athletic power in a group of non-smokers.
Regular moist snuff dipping does not affect endurance exercise performance
TLDR
In conclusion, endurance exercise performance (VO2max and maximal endurance time) does not seem to be affected by prolonged snuff use, while effects on cardiovascular risk factors are contradictory.
...
1
2
3
4
...

References

SHOWING 1-10 OF 38 REFERENCES
The effect of nicotine and carbon monoxide on exercise performance in normal subjects.
TLDR
In a partially blind randomized control study, nine healthy adult men performed progressive sub-maximal exercise tests, either after chewing nicotine chewing gum or breathing carbon monoxide, despite a mean rise in blood nicotine and COHb.
The effects of oral smokeless tobacco on the cardiorespiratory response to exercise.
TLDR
Data indicate that the increased Nc incurred by OST usage increases anaerobic energy production and produces an increased tachycardiac response to a given relative submaximal workload.
Effects of nicotine on perceived exertion during low-intensity activity.
TLDR
Results indicated no significant effect of nicotine on RPE for either males or females, and nicotine significantly increased each cardiovascular measure during activity, confirming that cardiovascular responses during exercise do not mediate RPE.
The effect of amphetamines on selected physiological components related to athletic success.
TLDR
The results demonstrate that amphetamines have no effect on aerobic power, but further research will be necessary to clarify the drug's influence on muscular power-dominated movements.
Metabolic, catecholamine, and exercise performance responses to various doses of caffeine.
TLDR
The results are not compatible with the traditional theory that caffeine mediates its ergogenic effect via enhanced catecholamines, and only the highest dose of caffeine resulted in increases in glycerol and free fatty acids.
Nicotine enhances the circulatory effects of adenosine in human beings
TLDR
It is concluded that the characteristic hemodynamic response to adenosine infusion is enhanced by nicotine, and the rise in plasma noradrenaline levels during the combined administration of nicotine andAdenosine differed significantly from the response to nicotine alone.
The effect of different dosages of caffeine on endurance performance time.
TLDR
It is concluded that caffeine is an ergogenic aid that stimulates endurance performance and a dose-response relation between caffeine and endurance time was not found for the dose-range investigated.
The effect of nicotine on energy expenditure during light physical activity.
TLDR
It is concluded that the relatively small metabolic effect of nicotine when the subject is at rest is enhanced during light exercise, suggesting that the weight gain that often follows smoking cessation may be influenced not only by nicotine intake but also by the level of physical activity a smoker typically engages in while smoking.
Responses to exercise in the heat related to measures of hypothalamic serotonergic and dopaminergic function
TLDR
The results suggest that high activity of the dopaminergic pathways in the hypothalamus is a predictor of exercise tolerance in the heat.
Effect of caffeine ingestion on perception of effort and subsequent work production.
TLDR
The data suggest that caffeine may play an ergogenic role in exercise performance by altering both neural perception of effort and substrate availability and there were no significant differences between the conditions in respiratory exchange ratio.
...
1
2
3
4
...