Effect of topical basic fibroblast growth factor on the healing of chronic diabetic neuropathic ulcer of the foot. A pilot, randomized, double-blind, placebo-controlled study.

@article{Richard1995EffectOT,
  title={Effect of topical basic fibroblast growth factor on the healing of chronic diabetic neuropathic ulcer of the foot. A pilot, randomized, double-blind, placebo-controlled study.},
  author={J L Richard and C Parer-Richard and J. P. Daur{\`e}s and S Clouet and Denyse Vannereau and Jacques Bringer and Michel Rodier and Carolyn Jacob and M Comte-Bardonnet},
  journal={Diabetes care},
  year={1995},
  volume={18 1},
  pages={64-9}
}
OBJECTIVE To assess the efficacy and safety of topical human recombinant basic fibroblast growth factor (bFGF) on the healing of diabetic neurotrophic foot ulcers. RESEARCH DESIGN AND METHODS Seventeen diabetic patients suffering from chronic neuropathic ulcer of the plantar surface of the foot entered a pilot, randomized, double-blind study comparing local application of bFGF with placebo. Main inclusion criteria were a typical neuropathic ulcer of Wagner grade I-III, more than 0.5 cm in the… CONTINUE READING
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