Effect of topical application of mitomycin-C on wound healing in a postlaminectomy rat model: an experimental study.


The aim of this study was to investigate the effects of topical application mitomycin-C (MMC) on wound healing after laminectomy. 60 adult male SD rats were equally and randomly divided into five groups. Laminectomy was performed at the level of L1 in all rats. After hemostasis was achieved, cotton pads soaked with saline and MMC (0.1mg/ml, 0.3mg/ml, 0.5mg… (More)
DOI: 10.1016/j.ejphar.2011.10.028