Effect of tissue preservation on imaging using ultrahigh resolution optical coherence tomography.

@article{Hsiung2005EffectOT,
  title={Effect of tissue preservation on imaging using ultrahigh resolution optical coherence tomography.},
  author={Pei-Lin Hsiung and Prashant R. Nambiar and James G. Fujimoto},
  journal={Journal of biomedical optics},
  year={2005},
  volume={10 6},
  pages={064033}
}
Ultrahigh resolution optical coherence tomography (OCT) is an emerging imaging modality that enables noninvasive imaging of tissue with 1- to 3-microm resolutions. Initial OCT studies have typically been performed using harvested tissue specimens (ex vivo). No reports have investigated postexcision tissue degradation on OCT image quality. We investigate the effects of formalin fixation and commonly used cell culture media on tissue optical scattering characteristics in OCT images at different… CONTINUE READING