Effect of timing of pharmaconutrition (immunonutrition) administration on outcomes of elective surgery for gastrointestinal malignancies: a systematic review and meta-analysis.

@article{Osland2014EffectOT,
  title={Effect of timing of pharmaconutrition (immunonutrition) administration on outcomes of elective surgery for gastrointestinal malignancies: a systematic review and meta-analysis.},
  author={Emma J Osland and Md. Belal Hossain and Shahjahan Khan and Muhammed Ashraf Memon},
  journal={JPEN. Journal of parenteral and enteral nutrition},
  year={2014},
  volume={38 1},
  pages={
          53-69
        }
}
BACKGROUND Pharmaconutrition has previously been reported in elective surgery to reduce postoperative infective complications and duration of hospital length of stay. OBJECTIVE To update previously published meta-analyses and elucidate potential benefits of providing arginine-dominant pharmaconutrition in surgical patients specifically with regard to the timing of administration of pharmaconutrition. DESIGN Randomized controlled trials comparing the use of pharmaconutrition with standard… 

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A critical re-appraisal of the use and recommendations of pharmaconutrition in this group of patients is urgently warranted to resolve some of the above mentioned issues.

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Meta-analyses Optimal postoperative nutrition support for patients with gastrointestinal malignancy : A systematic review and meta-analysis

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