Effect of timing and route of administration of furosemide on pulmonary hemorrhage and pulmonary arterial pressure in exercising thoroughbred racehorses.

@article{Lester1999EffectOT,
  title={Effect of timing and route of administration of furosemide on pulmonary hemorrhage and pulmonary arterial pressure in exercising thoroughbred racehorses.},
  author={G D Lester and Christopher M. Clark and Barbara Rice and C Steible-Hartless and T S Vetro-Widenhouse},
  journal={American journal of veterinary research},
  year={1999},
  volume={60 1},
  pages={22-8}
}
OBJECTIVES To examine effect of pre-exercise administration of furosemide (FUR) on mean pulmonary arterial pressure (PAP) during work and RBC concentration in bronchoalveolar lavage fluid (BALF) collected 40 minutes after exercise. ANIMALS 10 adult Thoroughbreds. PROCEDURE A modified 10 X 10 crossover design comprising 10 horses during 10 weeks was used. Each horse received each of 5 treatments twice. Treatment structure included a control plus a 2 X 2 factorial and consisted of the… CONTINUE READING

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