Effect of thyroxine on the activity of mitochondrial cardiolipin synthase in rat liver.

@article{Hostetler1991EffectOT,
  title={Effect of thyroxine on the activity of mitochondrial cardiolipin synthase in rat liver.},
  author={KarlY. Hostetler},
  journal={Biochimica et biophysica acta},
  year={1991},
  volume={1086 1},
  pages={
          139-40
        }
}
Cardiolipin is a major mitochondrial membrane lipid and plays a vital role in mitochondrial function. The effect of thyroxine on the activity of liver mitochondrial cardiolipin synthase was examined in this study. Treatment with thyroxine (250 micrograms/100 g) for 5 days increased cardiolipin synthase activity by 52%. Mitochondrial levels of cardiolipin appear to be regulated in part by the effect of thyroid hormone on the activity of cardiolipin synthase. 
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