Effect of thrombolysis on acute mitral regurgitation during evolving myocardial infarction: Experience from the thrombolysis myocardial infarction (TIMI) trial☆

@article{Lehmann1993EffectOT,
  title={Effect of thrombolysis on acute mitral regurgitation during evolving myocardial infarction: Experience from the thrombolysis myocardial infarction (TIMI) trial☆},
  author={Kenneth G. Lehmann and Charles K. Francis and Florence H. Sheehan and Harold T. Dodge},
  journal={Journal of the American College of Cardiology},
  year={1993},
  volume={22 3},
  pages={714-9}
}
OBJECTIVES This study was undertaken to determine whether early successful thrombolysis can reverse infarct-associated mitral valve dysfunction. BACKGROUND Mitral regurgitation is a common complication of acute myocardial infarction and has been shown to adversely affect both short- and long-term prognosis. Although anecdotal reports have suggested that reperfusion of the infarct-related artery may restore normal function to the mitral valve, this theory has not been subjected to formal… CONTINUE READING