Effect of thrombin on cyclic AMP content in glomeruli isolated from rat kidney.

@article{Shah1989EffectOT,
  title={Effect of thrombin on cyclic AMP content in glomeruli isolated from rat kidney.},
  author={Sudhir V. Shah},
  journal={Kidney international},
  year={1989},
  volume={35 3},
  pages={824-9}
}
Localized thrombin-mediated intravascular coagulation has been implicated as an important pathogenetic factor in a variety of glomerular and vascular diseases of the kidney. Recent studies indicate that glomerular function is affected by several hormonal agents which alter the cyclic AMP or cyclic GMP content in the glomeruli. Although thrombin has been shown to affect several metabolic processes in other cellular systems the possibility that thrombin may cause a reduction in glomerular… CONTINUE READING