Effect of the ratio of free to total prostate-specific antigen on interassay variability in proficiency test samples.


BACKGROUND Up to sevenfold differences were observed between total prostate-specific antigen (PSA) methods for New York State Proficiency Test samples prepared with seminal fluid PSA in human female serum. Because the PSA was mainly in its free form under these conditions, we wanted to determine whether a defined mixture of free and complexed PSA would… (More)


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