Effect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity

@article{Lee2015EffectOT,
  title={Effect of the protein corona on nanoparticles for modulating cytotoxicity and immunotoxicity},
  author={Yeon Kyung Lee and Eun-Ju Choi and Thomas Jay Webster and Sang-Hyun Kim and Dongwoo Khang},
  journal={International Journal of Nanomedicine},
  year={2015},
  volume={10},
  pages={97 - 113}
}
Although the cytotoxicity of nanoparticles (NPs) is greatly influenced by their interactions with blood proteins, toxic effects resulting from blood interactions are often ignored in the development and use of nanostructured biomaterials for in vivo applications. Protein coronas created during the initial reaction with NPs can determine the subsequent immunological cascade, and protein coronas formed on NPs can either stimulate or mitigate the immune response. Along these lines, the… 
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