Effect of the oral administration of tryptophan‐free amino acid mixtures on serum tryptophan, brain tryptophan and serotonin metabolism

@article{Gessa1974EffectOT,
  title={Effect of the oral administration of tryptophan‐free amino acid mixtures on serum tryptophan, brain tryptophan and serotonin metabolism},
  author={G. Gessa and G. Biggio and F. Fadda and G. Corsini and A. Tagliamonte},
  journal={Journal of Neurochemistry},
  year={1974},
  volume={22}
}
  • G. Gessa, G. Biggio, +2 authors A. Tagliamonte
  • Published 1974
  • Chemistry, Medicine
  • Journal of Neurochemistry
  • TRYPTOPHAN (Try) is the only amino acid circulating in plasma which is bound to serum proteins (MCMENAMY & ONCLEY, 1958). Previous studies from our (TAGLIAMONTE et al., 1971a; GESSA et al., 1972; TAGLIAMONTE et al., 1973a; 1973b) and Curzon's laboratories (KNOTT & CURZON, 1972) have shown that the concentration of free Try in serum parallels in many instances the concentration of Try in brain which, in turn, parallels the synthesis rate of brain serotonin (TAGLIAMONTE et al., 1971~; TAGLIAMONTE… CONTINUE READING
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