Effect of the mouse Nramp1 genotype on the expression of IFN-gamma gene in early response to Salmonella infection.

@article{Lalmanach2001EffectOT,
  title={Effect of the mouse Nramp1 genotype on the expression of IFN-gamma gene in early response to Salmonella infection.},
  author={A C Lalmanach and Agn{\`e}s Montagne and Pierrette Menanteau and Fr{\'e}d{\'e}ric Lantier},
  journal={Microbes and infection},
  year={2001},
  volume={3 8},
  pages={639-44}
}
The early interferon-gamma (IFN-gamma) response after Salmonella infection was compared in resistant and susceptible congenic mice strains differing by the allele of Nramp1. IFN-gamma gene expression in vivo was studied by quantitative reverse transcription-PCR performed from the spleen of mice challenged by Salmonella either in multiplication or in resting phase. The spleen colonisation by Salmonella in vivo was investigated and was shown to be identical in a genetically defined host, whatever… CONTINUE READING

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