Effect of the innate immune response on development of Theiler’s murine encephalomyelitis virus-induced demyelinating disease

Abstract

Theiler’s murine encephalomyelitis virus (TMEV) infection of susceptible mice leads to the development of demyelinating disease in the central nervous system (CNS) associated with an inflammatory immune response. The demyelinating disease in mice has similarities to multiple sclerosis in humans and is used as an experimental model for the human disease. The… (More)
DOI: 10.1007/s13365-014-0262-6

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