Effect of the immune modulators BM 12.531 (azimexone) and BM 41.332 on the subsets of T-lymphocytes in mice.

@article{Olsson1981EffectOT,
  title={Effect of the immune modulators BM 12.531 (azimexone) and BM 41.332 on the subsets of T-lymphocytes in mice.},
  author={L. Olsson and U. Bicker},
  journal={Journal of immunopharmacology},
  year={1981},
  volume={3 3-4},
  pages={
          277-88
        }
}
The immunomodulating 2-cyanaziridine derivatives BM 12.531 (azimexone) and BM 41.332 have no effects on the total amount of T-lymphocytes in the spleen of mice but increase dose-dependently the percentage of Ly1-, 2+, 3+ T-lymphocytes (killer/suppressor) and decrease the percentage of Ly1+, 2-, (helper) cells. These investigations were carried out by means of specific monoclonal antibodies and fluorescence-activated cell sorting. The increase in Ly2+-cells is mainly due to increased suppressor… Expand

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