Effect of the estrous cycle and surgical ovariectomy on energy balance, fuel utilization, and physical activity in lean and obese female rats.

@article{Giles2010EffectOT,
  title={Effect of the estrous cycle and surgical ovariectomy on energy balance, fuel utilization, and physical activity in lean and obese female rats.},
  author={Erin D Giles and Matthew R. Jackman and Ginger C. Johnson and Pepper J. Schedin and Jordan L. Houser and Paul S Maclean},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2010},
  volume={299 6},
  pages={R1634-42}
}
This study presents an in-depth analysis of the effects of obesity on energy balance (EB) and fuel utilization in adult female rats, over the estrous cycle and immediately after surgical ovariectomy (OVX), to model pre- and postmenopausal states, respectively. Female Wistar rats were fed a high-fat (46%) diet for 16 wk to produce mature lean and obese animals. Stage of estrous was identified by daily vaginal lavage, while energy intake (EI), total energy expenditure (TEE), and fuel utilization… CONTINUE READING
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