Effect of the degree of fatty acid unsaturation of rat heart mitochondria on their rates of H2O2 production and lipid and protein oxidative damage.

@article{Herrero2001EffectOT,
  title={Effect of the degree of fatty acid unsaturation of rat heart mitochondria on their rates of H2O2 production and lipid and protein oxidative damage.},
  author={Alicia Herrero and Manuel Portero-Ot{\'i}n and Mar{\'i}a Josep Bellmunt and Reinald Pamplona and Gustavo Barja},
  journal={Mechanisms of ageing and development},
  year={2001},
  volume={122 4},
  pages={427-43}
}
Previous comparative studies have shown that long-lived animals have lower fatty acid double bond content in their mitochondrial membranes than short-lived ones. In order to ascertain whether this trait protects mitochondria by decreasing lipid and protein oxidation and oxygen radical generation, the double bond content of rat heart mitochondrial membranes… CONTINUE READING