Effect of the cannabinoid ajulemic acid on rat models of neuropathic and inflammatory pain.

@article{Mitchell2005EffectOT,
  title={Effect of the cannabinoid ajulemic acid on rat models of neuropathic and inflammatory pain.},
  author={Vanessa A Mitchell and Sevda C Aslan and Reza Safaei and Christopher W Vaughan},
  journal={Neuroscience letters},
  year={2005},
  volume={382 3},
  pages={231-5}
}
There is increasing evidence that cannabinoid agonists alleviate the abnormal pain sensations associated with animal models of neuropathic and inflammatory pain. However, cannabinoids produce a number of motor and psychotropic side effects. In the present study we found that systemic administration of the cannabinoid acid derivative 1',1'-dimethylheptyl-delta-8-tetrahydrocannabinol-11-oic acid (ajulemic acid, IP-751) and the non-selective cannabinoid receptor agonist HU-210 reduced mechanical… CONTINUE READING
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