Effect of the antihistaminic agents meclastine and dexchlorpheniramine on the response of human growth hormone to arginine infusion and insulin hypoglycemia.

@article{Pontiroli1976EffectOT,
  title={Effect of the antihistaminic agents meclastine and dexchlorpheniramine on the response of human growth hormone to arginine infusion and insulin hypoglycemia.},
  author={A. Pontiroli and G. Viberti and A. Vicari and G. Pozza},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1976},
  volume={43 3},
  pages={
          582-6
        }
}
  • A. Pontiroli, G. Viberti, +1 author G. Pozza
  • Published 1976
  • Medicine
  • The Journal of clinical endocrinology and metabolism
  • Histamine is found in most tissues including the central nervous system. Here it reaches the highest concentrations in the hypothalamus and in the median eminence. In order to evaluate the possible role of endogenous histamine in the control of human growth hormone (hGH) secretion, we investigated the effect of two anti-histamine drugs, meclastine and dexchlorpheniramine, on the hGH response to arginine infusion and to insulin hypoglycemia in 30 normal subjects. The oral administration of… CONTINUE READING
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